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Pamela P Martinez

Assistant Professor, Microbiology
Assistant Professor, Statistics
Carl R. Woese Institute for Genomic Biology

Research Interests

Computational Biology, Host-Pathogen Interactions, Population dynamics

Research Description

In most pathogens, epidemiological and evolutionary processes occur on similar time scales due to the large population sizes and short generation times. This makes infectious diseases amenable to study and the interplay of their ecology and evolution particularly relevant for both fundamental biology and applied public health. However, temporal and spatial changes in infectious disease dynamics are difficult to anticipate due to the effects of environmental drivers on the transmission of pathogens and the complex diversity that these microorganisms exhibit. To address these challenges, my research on the ecology and evolution of infectious diseases focuses on the following general questions:

(1) How do demographic and climate factors shape the population dynamics of infectious diseases in space and time? and (2) How does pathogen diversity interact and interfere with public health interventions?

For answering these questions, I use mathematical and computational tools that are applied to different types of time series data from different parts of the world, including Bangladesh and Chile

Additional Campus Affiliations

Assistant Professor, Microbiology
Assistant Professor, Statistics
Assistant Professor, Center for Latin American and Caribbean Studies

Recent Publications

Mahmud, A. S., Bhattacharjee, J., Baker, R. E., & Martinez, P. P. (2024). Alarming trends in dengue incidence and mortality in Bangladesh. The Journal of infectious diseases, 229(1), 4-6. Article jiad529.

Larsen, S. L., Shin, I., Joseph, J., West, H., Anorga, R., Mena, G. E., Mahmud, A. S., & Martinez, P. P. (2023). Quantifying the impact of SARS-CoV-2 temporal vaccination trends and disparities on disease control. Science Advances, 9(31), Article eadh9920.

Mahmud, A. S., Martinez, P. P., & Baker, R. E. (2023). The impact of current and future climates on spatiotemporal dynamics of influenza in a tropical setting. PNAS Nexus, 2(9), Article pgad307.

Ke, R., Martinez, P. P., Smith, R. L., Gibson, L. L., Mirza, A., Conte, M., Gallagher, N., Luo, C. H., Jarrett, J., Zhou, R., Conte, A., Liu, T., Farjo, M., Walden, K. K. O., Rendon, G., Fields, C. J., Wang, L., Fredrickson, R., Edmonson, D. C., ... Brooke, C. B. (2022). Daily longitudinal sampling of SARS-CoV-2 infection reveals substantial heterogeneity in infectiousness. Nature Microbiology, 7(5), 640-652.,

Ke, R., Martinez, P. P., Smith, R. L., Gibson, L. L., Achenbach, C. J., McFall, S., Qi, C., Jacob, J., Dembele, E., Bundy, C., Simons, L. M., Ozer, E. A., Hultquist, J. F., Lorenzo-Redondo, R., Opdycke, A. K., Hawkins, C., Murphy, R. L., Mirza, A., Conte, M., ... Brooke, C. B. (2022). Longitudinal Analysis of SARS-CoV-2 Vaccine Breakthrough Infections Reveals Limited Infectious Virus Shedding and Restricted Tissue Distribution. Open Forum Infectious Diseases, 9(7), Article ofac192.

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